It is worth noting that our model, which was derived from 140 PDXs of different tumor types (i.e., 38 BRCA, 42 COADREAD, 25 NSCLC, and 35 PDAC), did not show a significant tendency towards co-occurrence of PIK3CA and the 11q13 amplicon (OR 2.69, p value 0.26). This evidence concerns the gene PIK3CA and non-small cell lung carcinoma.