CR1 and early-onset autosomal dominant Alzheimer disease: Critically, the long form of CR1, CR1-B, the reported risk allele for Alzheimer’s disease, was associated with a DE gene signature indicating upregulation of pathways labelled ‘cellular infiltration by leukocytes’ and ‘infiltration by neutrophils’; we thus speculate that the association of CR1long with AD might be explained at least in part, by altered immune cell infiltration into the brain.