Accordingly, mAbs were isolated from rhesus macaques: (1) post-immunization with BG505 SOSIP, the high titer nAb group, but pre-SHIV challenge (IMM), (2) post-SHIV infection, the high nAb titer group, in which animals became infected (INF), (3) post SHIV challenge, high nAb titer group, in which animals did not become infected (NON-INF), and (4) unimmunized and SHIV infected (NI, natural infection). Here, CBLIF is linked to infection.