INS and Insulin resistance: The results showed that: compared with the Control group, the blood sugar of the STZ group and STZ+H2S group were significantly increased (P<0.05) (Table 1), suggesting diabetic glucose tolerance; at the same time, we also found that the fasting blood glucose, fasting insulin level and insulin resistance index of the STZ group and STZ+H2S group were significantly Elevated (P<0.05) (Table 2); the above results suggest that the type 2 diabetes model was successfully constructed.