CCND1 and breast cancer: For example, the median values of B cells (−0.1870 vs. −0.1691, P < 0.001), T cells (−0.2160 vs. −0.1935, P = 0.0090), CD8+ T cells (0.0914 vs. 0.1009, P < 0.001), and DC cells (−0.1810 vs. −0.1465, P = 0.0170) were significantly attenuated in the CCND1 amplification group in breast cancer, while Th2 cells (0.05419 vs. 0.0148, P < 0.001) and MDSCs (0.0051 vs. −0.0198, P = 0.0094) appear upregulated (Figure S4).