Comparison of CCND1 amplification in 10,606 patients from the TCGA database and 10,109 patients from the MSKCC database revealed that ESCA and breast carcinoma had the highest incidence in the TCGA patients at 34.78% (64/184) and MSKCC patients at 18.55% (228/1,229) databases, respectively (Figure 1A). The gene discussed is CCND1; the disease is breast carcinoma.