To further confirm the role of all m6A regulators in HCC, we systematically investigated the expression of 13 m6A regulators (including six writers: KIAA1429, METTL3, METTL14, RBM15, WTAP, and ZC3H13; two erasers: ALKBH5 and FTO; and five readers: HNRNPC, YTHDC1, YTHDC2, YTHDF1, and YTHDF2) in 403 HCC samples and 58 adjacent normal tissue samples from the TCGA database. Here, METTL3 is linked to hepatocellular carcinoma.