SLC2A1 and cerebellar ataxia: Therefore, GLUT1 dysfunction contributes to a variety of CNS diseases, termed GLUT1-deficiency syndromes (Glut1-DS), such as drug-resistant epileptic seizures, psychomotor retardation, ataxia, and microcephaly (Galochkina et al., 2019; Koch and Weber, 2019).