The gene encoding products of AREs and GREs, such as C-MYC, Epidermal Growth Factor (EGF), Prostaglandin-Endoperoxide Synthase 2 (PTGS2), Proto-Oncogene C-Jun (JUN), and Proto-Oncogene C-Fos (FOS), are closely related to tumor processes such as cell growth, apoptosis resistance, angiogenesis, invasion, and metastasis (14, 15). Here, EGF is linked to neoplasm.