Of note, at 6 h post-infection, the induction of the gene encoding 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) a member of the of phosphofructokinase (PFK)-2 family, was more prominent in CDC1551-infected BMDMs (65). Here, PFKFB3 is linked to infection.