BRCA1 and cancer: In addition, we also observed that, independently of BRCA-mutational status, the second basal-like TNBC cell line MDA-MB-468, carrying normal levels of BRCA1 transcript despite allelic loss, and low expression of ATM, did show a high sensitivity to Olaparib (IC5072h 33.81 μM, 95%CI = 31.24–36.60), consistent with previous findings supporting this cell's BRCAness phenotype (49), and confirming that HR deficiency might be exploited to get a cancer cell response beyond BRCA-mutations.