ALB and COVID-19: In a recent meta-analysis Lippi et al., demonstrated that hepatic factors that were predictive of patients with an unfavorable course of COVID-19 requiring ICU admission included an increase in levels of ALT (1.5–1.8-fold), AST (1.8-fold), total bilirubin (1.2–1.3-fold) and decreased albumin (0.8-fold) (48).