In contrast, the A375 cells grew faster in the KD+OE group than in the KD+NC group (4.91 ± 0.05 vs. 2.93 ± 0.05, P = 0.001) (Figure 7B), indicating that the proliferation of DDX39-knockdown melanoma cells can be stimulated by SNAIL overexpression. The gene discussed is SNAI1; the disease is melanoma.