As shown in Figure 8, the transwell migration experiments showed that the numbers of cells detected in the lower chamber in the NC+NC group, KD+NC group, and KD+OE group were 109 ± 7.22, 40 ± 1.60, and 91 ± 0.39, respectively, indicating that the migration of DDX39-knockdown melanoma cells can be promoted by SNAIL overexpression (P < 0.001). This evidence concerns the gene SNAI1 and melanoma.