Studies have given promising evidence that NAC may normalize levels of hepatic malondialdehyde and superoxide dismutase (SOD) providing further insight that there could be a role in preventing obesity associated co-morbidities of the liver including NASH (Thong-Ngam et al., 2007; Korou et al., 2014). Here, SOD1 is linked to obesity due to melanocortin 4 receptor deficiency.