Recent in vivo studies in models of obesity and human studies have indicated that αT supplementation was capable of attenuating inflammatory processes by reducing the expression of IL-6, TNF-α, malondialdehyde and C reactive protein while increasing antioxidant constituents (Patrick and Uzick, 2001; Wong et al., 2017). The gene discussed is TNF; the disease is obesity due to melanocortin 4 receptor deficiency.