To confirm the importance of Salmonella-specific memory CD4 T cells in the protection to virulent Salmonella infection, some of the Se-2W-infected mice were depleted of CD4 T cells (using the anti-CD4 mAb GK1.5) prior to a second infection of virulent Se-2W (Figure 6A). The gene discussed is CD4; the disease is Salmonella Infections.