In contrast to the aforementioned similar attrition of naïve and memory CD8 T cells after sepsis, it was recently suggested by Xie et al. that CD44hi CD8 T cells in “memory mice” (generated via Listeria and LCMV infection) exhibited significant attrition after CLP while this was not the case for naïve CD44lo CD8 T cells (73). Here, CD8A is linked to Sepsis.