MYCN and neuroblastoma: In addition to TH-MYCN-derived tumors, other tumors derived from murine cell lines, such as neuro-2a (spontaneous NB from strain A albino mice, C1300 derived), TBJ (C1300, a strain A/J spontaneous tumor), 9464D (TH-MYCN on a C57Bl/6) and NXS2 (created from C1300 tumors) have been engrafted both subcutaneously and orthotopically for testing of immunotherapeutics [62–64].