HDAC2 and hepatocellular carcinoma: For example, Ler et al. (2015) showed that HDAC1 and HDAC2 could independently predict mortality of HCC using a competing risk regression model; Ji et al. (2019) suggested that HDAC3 deficiency enhanced liver cancer; Fan et al. (2014) discovered that knockdown of HDAC5 suppressed growth of HCC by induction of apoptosis and cell cycle arrest; Gong et al. (2019) suggested that inhibition of HDAC11 could promote apoptosis of human liver cancer.