NETs were reported to promote arterial and venous thrombosis [81], and high levels of all three markers of NETs (cell-free DNA, MPO-DNA, and Cit-H3) were detected in the serum of COVID-19 patients, with cell-free DNA and MPO-DNA levels significantly higher in patients requiring mechanical ventilation versus inpatients breathing room air [82]. This evidence concerns the gene MPO and Venous thrombosis.