SHMT2 and neoplasm: Here we analyzed expression of SHMT2, and 12 additional enzymes involved in serine/glycine/1-carbon metabolism in a NSCLC primary tumor, a cognate PDX model, cell line LPC43 that was derived from the PDX, and the established lung-adenocarcinoma-derived cell line HCC827 (Fig 1A, S2 Table in S1 Data).