As far as the tumor-associated expressional profile of the CCR5 axis is concerned, the majority of available data indicate induction of this chemokine network with a pro-tumor role and shorter overall survival rate in CRC (Cambien et al. 2011; Erreni et al. 2009; Nishikawa et al. 2019; Zhang et al. 2018; Zimmermann et al. 2010). Here, CCR5 is linked to neoplasm.