Analysis of the breast cancer dataset available through The Cancer Genome Atlas (TCGA) and GTEx database confirmed a marked increase in UNC5B expression in breast cancer compared to normal breast tissues (p < 0.05), whereas there were no significant differences in UNC5A, UNC5C, and UNC5D expression between breast cancer and normal tissues (Figure 1B). The gene discussed is UNC5B; the disease is breast carcinoma.