Compared to the list AF susceptibility genes including the 328 eQTL target genes what we have identified and combined with the closest gene of GWAS index SNPs, only 10 genes including HCN4, KCND3, KCNJ5, KCNN3, PITX2, TBX5, ZFHX3, GJA1, SYNE2, SH3PXD2A, and PLN were found have bath rare variants and common variants related with AF. This evidence concerns the gene ZFHX3 and atrial fibrillation.