Thiazide was given with the clinical impression of nephrogenic diabetes insipidus, although no pathogenic variants were identified in AVPR2 and AQP2. EVIDENCE suggested c.1679 T > C (p.Leu560Pro) and c.382C > T (p.Arg128Ter) in SLC12A1; subsequently, she was confirmed as having Bartter syndrome, type 1, and discontinued unnecessary medications. This evidence concerns the gene AQP2 and nephrogenic diabetes insipidus.