STAT3 and non-small cell lung carcinoma: Inhibition of circCELSR1 enhanced paclitaxel-induced cytotoxicity via upregulating FOXR2 expression or acting as the sponge for miR-1252 and increased cell apoptosis.119 Dong et al found that circ_0076305 was upregulated in NSCLC and promoted cisplatin resistance in NSCLC by upregulating STAT3 via targeting miR-296-5p.120