Importantly, YTHDF2 is not essential for normal hematopoietic stem cells, indicating that YTHDF2 is a unique therapeutic target which specifically inhibits LSCs.65 In cervical cancer, FTO was found to induce DNA repair activity and drug resistance to chemoradiotherapy by increasing β-catenin mRNA through m6A methylation.66 This evidence concerns the gene YTHDF2 and cervical cancer.