SLC8A1 and heart disorder: In addition, miR-135a-5p was found to be critical for exercise-induced adult neurogenesis (Pons-Espinal et al. 2019), by controlling NCX1 expression, miR-135a modulates cardiomyocyte automaticity, Ca2+ extrusion, and arrhythmogenic Ca2+loading/spontaneous Ca2+ release events to contribute to proarrhythmic remodeling after Complete atrioventricular block (Duong et al. 2017).