TGFB1 and myeloid sarcoma: For example, while L. paracasei DSM13434 and L. plantarum DSM 15312 increased TGF-β1 in the blood, L. plantarum DSM 15313 enhanced blood levels of IL-27.12 Until date the only probiotic considered a kind of medical food is Vivomixx23.Here, we proved the efficacy of Vivomixx treatment in a model of progressive MS whereby oral administration of this probiotic, during the chronic phase improved the motor disability likely associated to changes in gut microbiota.