There have also been a lot of contradictory data about the role of EMP1, epithelial membrane protein 1 (summarized in [37]); nevertheless, anti-migratory function of EMP1 in nasopharyngeal cancer cells [38] and its downregulation upon oral dysplasia progression to oral squamous cell carcinoma [39] have been documented; in addition, the mechanism for anti-lymphangiogenic effect of EMP1 through downregulation of VEGFC expression was proposed [38]. This evidence concerns the gene EMP1 and oral cavity squamous cell carcinoma.