HMGB2 and cervical cancer: Four genes encoding proteins with DNA-binding transcription factor-related activity (E2F7, HMGB2, MYBL2, and NSD2) and two genes encoding chromatin modifying enzymes (DNMT1 and UHRF1) showed elevated transcript levels in CR samples, of which MYBL2 and NSD2 were confirmed to function in pathways directly implicated in EMT in HPV(+) cervical cancer cells in in vitro studies [22,23,24].