As mentioned above, a greater number of DEGs (152 of 201) turned out to be downregulated in CR compared to CIN, with many known tumor suppressor genes (AR, PGR, FAT4, PTCH1, TGFBR3, HOPX, SASH1, CRYAB, CFTR, and CLCA4) or candidate tumor suppressor genes (PTPRM, PTPRU, SLIT2, LMO7, NEGR1, AIF1L, DEPTOR, and RHCG) found among them. The gene discussed is CFTR; the disease is cervical squamous intraepithelial neoplasia.