PMEL and melanoma: Similar anti-melanoma cancer activity was exerted by human T cells, including peripheral blood mononuclear cells, CD8+ T cells and γ/δ T cells, transfected with mRNA specific to either gp100/HLA-A2-TCRs or MCSP CARs against human melanoma cell lines A375M and Mel526, and the lymphoma cell line Daudi [39].