Although CEP72, Chromosome 1 Open Reading Frame 35 (C1orf35), Collagen Type XV α 1 Chain (COL15A1), Cysteine Rich Protein 3 (CRIP3), HLA Complex Group 25 (HCG25), HIG1 Hypoxia Inducible Domain Family Member 1B (HIGD1B), KRTCAP2, LOC105369632, MicroRNA 4793 (MIR4793), MSTO1, NTF3, and TBCE of the 34 DEGs have not been previously related to cancers, our study showed that they could be novel potential biomarkers of LIHC. This evidence concerns the gene CRIP3 and cancer.