Our results indicated that UBE2C was involved in cell invasion and migration in OSCC cells (Figure 3); higher UBE2C expression was associated with lymph node metastasis in OSCC patients (Supplementary Table S1) and with poor DSS in TSCC patients having lymph node metastasis (Table 3). This evidence concerns the gene UBE2C and metastatic malignant neoplasm in the lymph nodes.