GAD1 and brain ischemia: Cerebral ischemia and peptide 5 treatment were associated with significant overall changes in interneuron density in the parasagittal cortex (Figure 2, one-way ANOVA; GAD+, p = 0.013; parvalbumin+, p = 0.03; calretinin+, p = 0.001; and calbindin+, p = 0.04).