The following factors were below: Child–Pugh score ≤8 (n = 28) or >8 (n = 15); ALBI ≤−1.7 (n = 20) or >−1.7 (n = 23); FIB-4 ≤ 7.0 (n = 20) or >7.0 (n = 23); plasma AT-III ≥60 (n = 22) or <60 (n = 21); blood platelet count ≥8.0 × 104 (n = 19) or <8.0 × 104 (n = 24); PVT volume ≥3.0 mL (n = 20) or <3.0 mL (n = 23); history of splenectomy or PSE present (n = 7) or absent (n = 36); history of varices treatment present (n = 20) or absent (n = 23); and HCC diagnosis present (n = 16) or absent (n = 27). The gene discussed is SERPINC1; the disease is hepatocellular carcinoma.