At week 9, tumor volumes and tumor weights had significantly increased in both sphere (CSC-like) cell-implanted groups, especially the SP-CD133-implanted mouse group, compared to control mice implanted with SKOV3-P cells (n = 6 per group; *** p < 0.001 and * p < 0.05, respectively, Figure 4D,E). The gene discussed is PROM1; the disease is neoplasm.