Dose-dependent reduction of cell viability by wild type (WT) recombinant human TRAIL (rhTRAIL) in colon carcinoma cells was analyzed using [3-(4,5-dimethylthiazol-2-yl)-5-3(carboxymethoxyphenyl0-2-(4-sulfophenyl)-2H-tetrazolium] (MTS) assay. The gene discussed is TNFSF10; the disease is colon carcinoma.