Although certain biomarkers involved in extracellular matrix turnover such as matrix metalloproteinase-3 and monocyte chemoattractant protein-1 at baseline were highly associated with the pathophysiology of acute myocardial infarction, the serum levels of Gal-3 were not related to the left ventricular remodeling defined by cardiac MRI in patients showing cardiac dysfunction [67]. This evidence concerns the gene LGALS3 and acute myocardial infarction.