Multivariate analysis revealed that expression levels of 10 genes (EPS8, HMGA2, ENDOD1, SLC39A10, TGM2, MGLL, SERPINE1, ITGA2, DTL and UAUC) were independent prognostic factors for 5-year overall survival after adjustment for tumor stage, lymph node metastasis, and pathological stage (p < 0.01). The gene discussed is ENDOD1; the disease is metastatic malignant neoplasm in the lymph nodes.