This study characterized monocyte subtypes: classical, intermediate, and non-classical with the expression of surfaces markers: CD62L, CD11c, CD18, HLA-DR in non-small cell lung cancer patients (NSCLC) compared to healthy controls and correlations between monocyte subtypes and macrophages in the lung cancer microenvironment. Here, ITGB2 is linked to non-small cell lung carcinoma.