CXCL8 and infection: Urogenital infections [47]. Adhesion to epithelial cells promotes acute inflammation via triggering of innate immune sensors expressed on the cells’ surface. Activation of pro-inflammatory signals ultimately results in recruitment of leucocytes to the infection site. The recombinant C-terminal portion of the immunogenic protein MG309 (rMG309c) activates NF-κB via TLR2/6 in genital epithelial cells (EC), which in turn secreted proinflammatory cytokines, including interleukin-6 (IL-6) and IL-8 [109,110].