Similarly, iPS-RPE cells significantly suppressed IFN-γ production of Th1-type CD4+ uveitis T cells in patients with HLA-B27 associated acute anterior uveitis, acute retinal necrosis, CMV retinitis, sarcoidosis, VKH disease, and Behçet’s disease (Figure 1B). Here, CD4 is linked to Vogt-Koyanagi-Harada disease.