INS and hydrops fetalis: Analysis of trunk plasma insulin after 6 weeks of HF feeding revealed that WR females had higher plasma insulin than their Sed counterparts (M Sed 1.04 ± 0.10, M WR 0.54 ± 0.05, F Sed 0.44 ± 0.06, and F WR 0.69 ± 0.06 ng/mL; sex × exercise F (1,44) = 31.40, p < 0.001; post hoc female Sed vs. WR p < 0.05) whereas the opposite pattern was observed in Sed and WR males (post hoc p < 0.001).