CD8A and viral infectious disease: Conditional deletion of miR-181ab1 in peripheral T cells impaired the expansion of virus-specific CD8 T cells after acute LCMV infection and delayed viral clearance [102], mirroring T cell defects seen in old individuals in responses to infections such as with yellow fever, West Nile virus and likely the current SARS-CoV-2 [103,104,105,106].