BIRC5 and neoplasm: As shown in Figure 2, the results of the R2 megasampler analysis revealed that in all the independent GEO datasets analyzed, both YY1 and BIRC5 are significantly upregulated within the B-NHL patients datasets (T, Tumor) compared to healthy control ones (N, Normal; p < 0.0001; the complete statistics results are included in Table S3), thereby suggesting that the evaluation of the expression of these two genes may have a diagnostic value in suspicious cases or in individuals at risk for this pathology.