Moreover, by targeting matrix metalloproteinase 8 (MMP8), hepatoma-derived growth factor (HDGF), brain-specific angiogenesis inhibitors (BAIs), and other vascular-related genes, miRNA-214 contributes to the pathogenesis of various cardiovascular conditions, including ischaemic heart diseases, angiogenesis, and cardiac hypertrophy [41,42,43]. This evidence concerns the gene MMP8 and heart disorder.