Comparing the “long survivor” group and the rest of the SCA patients (ie, “stroke” and “random”), three genes exhibited unusual differentiation (Figure S8B), including CYP21A2, P2RY2 [MIM: 600041], and PLAT (P = 6.28 × 10−6, 1.22 × 10−5, and 1.97 × 10−5, respectively), enriched for blood coagulation (P = .0013) (Figures S9A, and S9C), associated with thrombophilia (P = .006818), and expressed in the liver (P = .0053). This evidence concerns the gene P2RY2 and autosomal dominant cerebellar ataxia.