In human leiomyosarcomas (LMS), expression of UBE2C was found in 12 of 26 (46%), of CENPE in 7 of 26 (27%), of HAS2 in 7 of 26 (25%) and of CREB3L2 in 20 of 27 (74%) human leiomyosarcoma cores (Fig 2B). This evidence concerns the gene HAS2 and leiomyosarcoma.