With regard to the study of T cells from patients with SLE, the involvement of PP2A in the immunopathogenesis of the disease appears to be even more complicated in view of the fact that the expression of PPP2R2B is decreased (20), whereas the expression of PPP2R2D is increased, as shown in this study. The gene discussed is PPP2R2B; the disease is systemic lupus erythematosus.