Ongoing studies at the National Cancer Institute (NCI) are evaluating the efficacy of NLG207 in combination with the PARP inhibitor, olaparib, in small-cell lung cancer, urothelial carcinoma, and prostate cancer, and with the androgen receptor antagonist, enzalutamide, in prostate cancer (NCT02769962 and NCT03531827, respectively). This evidence concerns the gene AR and prostate carcinoma.