Among pro-apoptosis genes, death receptor genes (TNFRSF9 and FAS), mitochondrial pathway related genes (caspase-9, cyt-c and apaf-1), Bcl-2 family pro-apoptosis genes (BAK1 and BID, inhibitors of the IAP family members) and p53-dependent target genes (CYFIP2), were upregulated at various time points after DTMUV infection. Here, APAF1 is linked to infection.