To ensure the accuracy of the results, we also compared the expression of all three chemokines in LUSC and LUAD cohorts from TCGA database, and found that the expressions of CXCR4, CXCR5 and CCR7 were higher in LUAD tumor tissues, which was consistent with our database, but the differences were not significant. Here, CXCR5 is linked to neoplasm.