TF and anemia (phenotype): The IVICA trial from Nottingham, UK, looked at 116 patients with anaemia undergoing colorectal cancer surgery and found that intravenous iron had no effect on blood transfusion use,18 whereas a smaller trial of 72 patients in Australia found that intravenous iron for patients with iron deficiency anaemia (ferritin <300 μg/L, transferrin saturation <25%) did reduce perioperative blood transfusion (12% vs 31%).19