According to the FISH results of tumor MYCN status (Table 2, Table S1), plasma MYCN/NAGK ratio was significantly higher in MYCN‐positive patients with NB than in negative patients, 69.07 (median CI 95%, 53.39, 142.50) vs 1.27 (median CI 95%, 1.00, 1.53). This evidence concerns the gene MYCN and neoplasm.